Just watched the last episode. And I'm now worried. Remember a few episodes ago with Gordon and the simulation of the woman on the phone? Remember what Kelly said? Without Ed, there'd be no Orville. The same is true without Kelly. Think about it: Ed only got command because Kelly put a word in for him, mostly out of regret for cheating on him. If she's never has a relationship with Ed, then that means Ed doesn't get a command, Gordon still stays on suspension, Finn never transfer to the Orville, Bortus never finds out Klyden was once female and willing goes along with the gender reassignment of their kid, all the female Moclans end up being converted, LaMarr is still playing dumb (or worse, lobotomized), a whole lot of people are dead (the scientists from the first episode, the two colonies Ed and Company saved from the Krill), and the two worse possible scenarios: Pria (remember her?) successfully steals the Orville and it's not there to stop the Kaylon (and since Isaac doesn't meet Finn, that means there's no one stopping the Kaylon from wiping out all living things, and without Kelly and Gordon to get the Krill involved, they sit it out until the Kaylon wipe them out). This is the worst Butterfly Effect scenario ever seen in any form of fiction.
Additional Edit: I just posted this in the WMG section of the Orville page on TV Tropes. I think this may be setting up next season to have it where the crew realize something's wrong and they have to go back and correct the timeline.